Dr Toufic Arnaout  (Bio)

Speaker and visitor at international events

Speaking at the Bernal Institute, Ireland

Speaking at the EuPAT and European Federation for Pharmaceutical Sciences, Austria

At the International Foundation -
Process Analytical Chemistry (IFPAC), USA

At the European Commission, Belgium

At the White House, USA

At the Frontiers in Materials Characterisation towards Industrial Translation

(FRIMACHAT), Ireland (first to the left)

At the MIT, USA

At Harvard, USA

At the International Conferences on the Crystallization of

Biological Macromolecules (ICCBM) (2nd from top right)

At a dairy plant, the EU

At the Advanced Photon Source (APS), USA

Visiting a new €6M Cryo-TEM, Ireland

At the Diamond Light Source synchrotron (DLS, UK)

At a food plant, the EU

At a pharma plant, Spain

With science professors in Qatar

With biotechnology professors in Singapore

Worked on private and public projects involving varying agencies, companies and institutions

  • Technological University Dublin (previously the DIT), Ireland - 2019
  • Dublin Institute of Technology (DIT), Ireland - 2014-2018
  • Dairy Processing Technology Centre (DPTC) - 2016
  • Washington University School of Medicine, USA - 2013
  • Trinity College Dublin, Ireland - 2009-2013
  • University Paris Orsay, France - 2008
  • University of Poitiers - 2007
  • Science Foundation Ireland (SFI)
  • European Commission FP7
  • Centre national de la recherche scientifique, France (CNRS)
  • National Institutes of Health, USA (NIH)
  • Studied at the universities of Poitiers, Paris V, Ecole Polytechnique, and Trinity College Dublin

Disclaimer: logos not owned by Kappa Crystals Ltd. Owners have no affiliation with Kappa Crystals Ltd.

Academic engagement

Senior authored papers:

  • Targeting lipoprotein biogenesis: considerations toward antimicrobials

Trends in Biochemical Sciences, 2019

 

  • The N-acyltransferase Lnt: structure-function insights from recent simultaneous studies

International Journal of Biological Macromolecules, 2018

 

  • Immersible optical imaging assembly for observing microparticles

filed patent, UK, GB1813034.4

 

  • 3D-360° micro-surface feature imaging of transparent particles

Scientific Reports, 2017

 

  • Structural basis of lipoprotein signal peptidase II action and inhibition by the antibiotic globomycin

Science, 2016

 

  • Crystallization monitoring using simultaneous Bright Field and PlasDIC imaging

Chemical Engineering Journal, 2016

 

  • A novel backlight probe and image algorithms for real time size-shape analysis during crystallization

Chemical Engineering Science, 2016

 

  • The crystal structure of a membrane peptidase bound to antibiotic (PDB: 5DIR)

The Protein Data Bank, 2016

Other work:

  • Rapid analysis of magnesium in infant formula powder using laser-induced breakdown spectroscopy

International Dairy Journal, 2019

 

  • Multipoint NIR spectrometry for real-time monitoring of protein conformation

International Journal of Food Sciences and Nutrition, 2015

 

  • A conformational landscape for alginate secretion across the outer membrane

Acta Crystallographica D, 2014

 

  • The αN helix of the archaeal XerA Tyrosine recombinase is a molecular switch of recombination

PLOS ONE, 2013

 

  • In meso structure of alginate transporter - crystal forms 1, 2 and 3 (PDB 4AZL, 4AFK, 4AZL)

Protein Data Bank, 2013

 

  • The structure of a dimeric recombinase (PDB: 4A8E)

Protein Data Bank, 2012

Meetings and invited talks

  • Frimachat and the EMCC (European Materials Characterisation Council), Bernal Institute, Ireland, 2017

             "Process analytical technology (PAT) for pharmaceutical and protein crystallization"

  • International Foundation Process Analytical Chemistry (IFPAC), USA, 2015

             "Developing a new PAT Device and Algorithms for the In situ Imaging of Crystallization"

  • 7th pan-European Science Conference on QbD and PAT Sciences (EuPAT), Austria, 2015

             "Towards greater crystallization process control using optical engineering techniques and algorithms"

  • Bernal Institute and the Solid State Pharmaceutical Centre (SSPC), Limerick, Ireland, 2017

             “Particle engineering in pharmaceutical and biological sciences”

  • Nanyang Technological University, Singapore, 2017

                   “Process analytical technology (PAT) and quality by design (QbD) for API and protein crystallization”

  • Hamad Bin Khalifa University, and Qatar Foundation, Qatar, 2017

                   “Process analytical technology (PAT) for pharmaceutical and protein crystallization”

  • School of Medicine, Washington University in St Louis, 2013

                   “Crystallization of membrane proteins using the lipidic cubic phase”

  • Talks on the structure and function of site-specific DNA recombinases"

                    at:   - Max Planck Institute, Friedrich Miescher Laboratory, Tübingen, Germany

                           - Paul Scherrer Institut (PSI), Switzerland

                           - Faculty of Medicine, University of Leuven, Belgium

                           - NKI, Amsterdam, Netherlands

                           - EPFL Polytechnique, Lausanne, Switzerland

                           - Leibniz Institute for Age Research, Fritz Lipmann Institute, Jena, Germany

Conference posters and abstracts

  • Pharmaceutical process analytical technology for the Industry 4.0

H2020 European Commission, Belgium, 2017 (proposed at a panel, parallel sessions)

 

  • Detecting offal adulteration in meat using Laser-induced breakdown spectroscopy (LIBS)

Food Factor I, Barcelona Conference, Spain, 2016

 

  • Multipoint NIR Spectroscopy for Moisture Content Determination of Powered Formula

IFPAC (pharmacy), USA, 2015

 

  • Multipoint NIRS: Overcoming the limitation of sample heterogeneity in static and motion conditions

ICEF12 (food tech.), Canada, 2015

 

  • Moisture content determination of powdered infant formula utilising multiprobe spectroscopy

ICEF12 (food tech.), Canada, 2015

 

  • Cloning, expression and purification of a prolipoprotein signal peptidase

Science Foundation Ireland visitors’ day, Ireland, 2011

  • Applying a GFP fusion-based expression system for crystallization and structural studies

ICCBM13, Ireland, 2010

Advanced training and certifications

Accomplished trainings such as: 

 

 

 

 

 

 

 

 

 

 

Awards and associateships, for example: 

- Entrepreneurship & Innovation at the DCU Ryan Academy, Ireland

- Business programme with the Enterprise Office, Ireland

- Licence to interview, Irish Times training, Ireland 

- Biological safety, Trinity College Dublin, Ireland

- Biacore training, GE Healthcare, Ireland
- Predoctoral schools with the University of Joseph Fourier, Grenoble, France
- Protein studies and radioactive methods, the Commission for Atomic Energy (CEA), France   
- Language certification, Georgetown University, USA
- Trainings at Medical analysis laboratories

- Technology Innovation Development Award (SFI-TIDA), Ireland
- Postdoc on EU FP7 and US NIH projects 
- PhD fellowship, Science Foundation Ireland
- Internship at the CNRS, France. Also one of fifteen selected for a MSc of Eng. of Biomolecules in Paris, France

toufic el arnaout

+353 (0) 89 95 08 104

 

info@kappacrystals.com

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